Christina Applegate asks if breast implants are behind symptoms after MS misdiagnosis

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U.S. actor Christina Applegate is questioning whether her breast implants could be contributing to her pain and fatigue. Experts say symptoms associated with breast implant illness can overlap with other conditions, so people experiencing them should seek a thorough medical evaluation before making decisions about their implants.

Actor Christina Applegate, 54, says she is exploring whether her breast implants could be linked to her pain and fatigue after learning she was misdiagnosed with multiple sclerosis (MS) — the diagnosis she received in 2021.

On the Nov. 10 episode of MeSsy, the podcast she co-hosts with actor Jamie-Lynn Sigler, Applegate, who first gained fame as a teen in the hit sitcom Married With Children, said someone had recently sent her a study describing breast implant-related symptoms as resembling MS.

"I swear, over the last five years or whatever, I thought, 'What if they're leaking and they're poisoning me?'" she said, noting she plans to discuss the possibility with her doctors.

Applegate underwent a double mastectomy and breast reconstruction in 2008 after being diagnosed with an early form of breast cancer and testing positive for a BRCA1 gene mutation, which carries a higher risk of breast and other cancers. On her podcast, she said she was "way overdue" to have her implants replaced.

She has also described worsening pain and difficulty moving her right shoulder, saying it can take her at least 10 minutes to sit up and get out of bed. Those symptoms, she said, are overwhelming because "there's so many different things that could be going on."

Her search comes after doctors told her in October that she does not have MS. At the time, Applegate said the news left her back at "Square 1," her physical struggles have continued and she's undergoing testing for other possible explanations, including rheumatoid arthritis, lupus and Lyme disease.

While the cause of Applegate's symptoms remains unknown, breast implants have been associated with illness in some cases, though the condition is not well understood.

Breast implant illness, or BII, is a term for symptoms reported by some people with implants, including fatigue, cognitive changes, joint pain and muscle pain. This photo shows a Biocell textured breast implant by Allergan. (Nicolas Amaya/CBC)

Breast implant illness, or BII, is…

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