Rams vs. Cardinals prediction, prop bets Week 10: LA’s rushing duo keeps Arizona winless at home

Detailed summary

The Cardinals have lost ten straight games at State Farm Stadium.

All eyes will be on Sean McVay and the Rams’ redesigned offense as they look to avenge an upset loss to the Cardinals from earlier in the season on Sunday.

The Rams are 9.5-point road favorites, and for the first time in nearly two seasons, Matthew Stafford will miss both members of his star-studded receiving tandem of Puka Nacua and Davante Adams.

Then there’s the dubious and head-scratching fact that the Cardinals have lost 10 straight games at State Farm Stadium.

With the Rams’ receiving corps out due to injury and uncertainty surrounding rookie Carson Beck under center, the total has been juiced down from its opening line of 47.5 to 39.5 at most books.

Now that Jacoby Brissett is a Raven and Gardner Minshew is on IR, Beck will make his NFL debut; what better way to welcome him than with a front seven led by Myles Garrett and Aaron Donald?

Leading target Trey McBride remains a safety net for Beck, but the bad news is that the Cardinals’ offensive line has surrendered 3 or more sacks in three straight games.

Garrett is coming off a hat trick in Week 9 against the Commanders, and the once-troubled Rams defense now ranks sixth in DVOA, including fourth against the run and eighth against the pass.

Arizona may try to establish the run and control time of possession, as it did in the first meeting. But with a first-year starter getting his debut reps behind a banged-up offensive line, that approach is unlikely to be as successful as it was last time.

Instead, I think the Rams will be better at establishing the run behind their running back duo of Kyren Williams and Blake Corum.

Opening of the article, excerpted from New York Post. To read the rest, open the article on the publisher's site.